s-23 sarm (Sarmabolic): Overview, Uses, Risks, and Considerations
s-23 sarm is an investigational Selective Androgen Receptor Modulator (SARM) developed for potential muscle-wasting disorders. Unlike anabolic steroids, SARMs selectively target androgen receptors in muscle and bone while aiming to reduce side effects on other organs. However, S-23 is not approved for human use and is classified as a research chemical.
1. What is s-23 sarm
- Mechanism: Binds to androgen receptors in muscle and bone, promoting anabolic (muscle-building) activity with reduced androgenic (e.g., prostate, hair) effects.
- Status: Preclinical studies only; abandoned in clinical development due to safety concerns.
- Legality: Banned by the World Anti-Doping Agency (WADA). Unapproved for human use in most countries.
2. Purported Benefits
- Muscle Growth: Potent anabolic effects, stronger than some SARMs (e.g., Ostarine).
- Fat Loss: May enhance metabolic rate via muscle preservation during cutting phases.
- Bone Density: Theoretical benefit for osteoporosis (no human data). s-23 sarm
3. How S-23 Works
- Mimics testosterone’s binding to androgen receptors in muscle and bone.
- Avoids activation of receptors in the prostate, liver, or hair follicles (in theory).
- Partial Agonism: May suppress natural testosterone production (like steroids).
4. Typical Dosage (Unofficial)
- Cycle Length: 6-8 weeks (due to strong suppression of natural testosterone).
- Dosing:
- Bulking: 10-20 mg/day (anecdotal reports).
- Cutting: 10-15 mg/day.
- PCT (Post-Cycle Therapy): Often required (e.g., SERMs like Clomid) to restore testosterone.
5. Side Effects & Risks
- Testosterone Suppression: Severe due to strong androgen receptor binding.
- Liver Toxicity: Elevated liver enzymes reported in users.
- Cardiovascular Risks: Potential HDL (“good” cholesterol) reduction and hypertension.
- Other: Acne, hair loss, aggression, and gynecomastia (from estrogen imbalance post-cycle).
- Unknown Long-Term Effects: No human safety studies.
6. Why Do People Use S-23?
- Bodybuilding: Anecdotal claims of rapid lean mass gains.
- Research Interest: Studied for muscle atrophy (animal models only).
- Availability: Sold online as a “research chemical,” despite legal risks.
7. Alternatives to S-23
- FDA-Approved Therapies: Testosterone Replacement Therapy (TRT) under medical supervision.
- Legal SARMs Alternatives: Natural muscle builders (e.g., creatine, DHEA).
- Lifestyle Strategies: Progressive overload training, optimized protein intake.
8. Why Avoid S-23?
- No Human Safety Data: Preclinical studies showed toxicity in animal models.
- Legal Risks: Classified as a controlled substance in some countries (e.g., the U.S. under the SARMs Control Act).
- Health Dangers: Liver damage, hormonal imbalances, and cardiovascular risks.
- Unregulated Market: Products may be mislabeled, underdosed, or contaminated.
9. Final Recommendations
- Avoid Use: The risks far outweigh unproven benefits.
- Seek Medical Advice: For muscle wasting or performance goals, consult a doctor.
- Natural Alternatives: Prioritize diet, training, and evidence-based supplements.
Disclaimer: S-23 is not intended for human consumption. This information is for educational purposes only. Using SARMs without medical supervision is illegal and hazardous.